Publikationen

Medizin 1

Direktor:
Prof. Dr. med. Markus F. Neurath

Nachwuchs - Arbeitsgruppe: Die Bedeutung von Neutrophil Extracellular Traps in der Immunreaktion chronisch entzündlichen Darmerkrankungen

Publikationen

Maueröder C, Mahajan A, Paulus S, Gößwein S, Hahn J, Kienhöfer D, Biermann MH, Tripal P, Friedrich RP, Munoz LE, Neurath MF, Becker C, Schett GA, Herrmann M, Leppkes M. Ménage-à-Trois: The Ratio of Bicarbonate to CO(2) and the pH Regulate the Capacity of Neutrophils to Form NETs. Front Immunol. 2016 Dec 9;7:583. doi:10.3389/fimmu.2016.00583. PubMed PMID: 28018350; PubMed Central PMCID:PMC5145884.

Bilyy R, Fedorov V, Vovk V, Leppkes M, Dumych T, Chopyak V, Schett G, Herrmann M. Neutrophil Extracellular Traps Form a Barrier between Necrotic and Viable Areas in Acute Abdominal Inflammation. Front Immunol. 2016 Oct 10;7:424. PubMed PMID: 27777576; PubMed Central PMCID: PMC5056318.

Hahn J, Knopf J, Maueröder C, Kienhöfer D, Leppkes M, Herrmann M. Neutrophils and neutrophil extracellular traps orchestrate initiation and resolution of inflammation. Clin Exp Rheumatol. 2016 Jul-Aug;34(4 Suppl 98):6-8. Review. PubMed PMID: 27586795.

Leppkes M, Maueröder C, Hirth S, Nowecki S, Günther C, Billmeier U, Paulus S, Biermann M, Munoz LE, Hoffmann M, Wildner D, Croxford AL, Waisman A, Mowen K, Jenne DE, Krenn V, Mayerle J, Lerch MM, Schett G, Wirtz S, Neurath MF, Herrmann M, Becker C. Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis. Nat Commun. 2016 Mar 11;7:10973. doi:10.1038/ncomms10973. PubMed PMID: 26964500; PubMed Central PMCID: PMC4793047.

Leppkes M, Ganslmayer M, Strauß R, Neurath MF. [Toxic megacolon]. Med Klein Intensivmed Notfmed. 2015 Oct;110(7):500-5. doi: 10.1007/s00063-015-0076-1. Review. German. PubMed PMID: 26369529.

Leppkes M, Neurath MF, Herrmann M, Becker C. Immune deficiency vs. immune excess in inflammatory bowel diseases-STAT3 as a rheo-STAT of intestinal homeostasis. J Leukoc Biol. 2016 Jan;99(1):57-66. doi: 10.1189/jlb.5MR0515-221R. Review. PubMed PMID: 26232455.

Leppkes M, Roulis M, Neurath MF, Kollias G, Becker C. Pleiotropic functions of TNF-α in the regulation of the intestinal epithelial response to inflammation. Int Immunol. 2014 Sep;26(9):509-15. doi: 10.1093/intimm/dxu051. Review. PubMed PMID: 24821262.

Pickert G, Neufert C, Leppkes M, Zheng Y, Wittkopf N, Warntjen M, Lehr HA, Hirth S, Weigmann B, Wirtz S, Ouyang W, Neurath MF, Becker C. STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing. J Exp Med. 2009 Jul 6;206(7):1465-72. doi: 10.1084/jem.20082683. PubMed PMID: 19564350;PubMed Central PMCID: PMC2715097.

Leppkes M, Becker C, Ivanov II, Hirth S, Wirtz S, Neufert C, Pouly S, Murphy AJ, Valenzuela DM, Yancopoulos GD, Becher B, Littman DR, Neurath MF. RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F. Gastroenterology. 2009 Jan;136(1):257-67.doi: 10.1053/j.gastro.2008.10.018. PubMed PMID: 18992745.

 

 

 
 
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