Offene Stellen

Medizin 1

Direktor:
Prof. Dr. med. Markus F. Neurath

 

Master/PhD/PostDoc position in Gastroenterology/Hepatology

Offered by

The Laboratory of

MUCOSAL INFECTION BIOLOGY

In Erlangen-Nürnberg, Germany

 

A Master/PhD/PostDoc position is available in the laboratory of Prof. Claudia Günther at the Experimental Unit of the Internal Medicine 1, UK Erlangen

Immune-based therapies and diagnostics have proven their enormous potential in the treatment of immune-mediated inflammatory diseases (IMIDs) such as inflammatory bowel disease (IBD), autoimmune hepatitis (AIH), rheumatoid arthritis (RA), multiple sclerosis (MS) and are currently revolutionizing medical practice across numerous disciplines, allowing for highly individualized therapy approaches. Insights into the underlying molecular disease mechanisms thus become increasingly important for researchers and clinicians alike. Common denominators of such diseases are progressive inflammation-driven tissue damage and consecutive dysfunction of the affected organs. Our group has been focusing on how tissue injury and the associated response mechanisms are modulated by the microenvironment with a particular interest on IMIDs of the liver (Günther et al., JCI 2016; He & Günther et al., Gut 2016, Bittel et al., Cell Death Dis. 2019) and the gut (Günther et al., Nature 2011, Wittkopf & Günther et al., Gastroenterology 2013; Günther et al., Gut 2013, Günther et al., Gastroenterology 2019). A strength of our group is our interdisciplinary and translational research approach, spanning the spectrum from basic cellular and molecular methods to pre-clinical models and the validation of our findings in a clinical setting using human material. Most of the research behind our increased understanding of IMIDs was carried out using preclinical ex-vivo organ culture models, known as organoids (Günther et al., Dig Liver Dis 2019). Accordingly, organoids represent a key technique of our laboratory.

We are looking for a curious and knowledge-driven student with a Diploma/Master degree in Molecular Medicine, Biology, Bioinformatics or related fields. Candidates should have a strong background in Gastroenterology, Hepatology, Stem Cell Biology or Bioinformatics. The doctoral researcher/postdoctoral fellow will be part of the DFG-TRR305, DFG-FOR2886 or DFG-FOR2441, which provides a structured curriculum with special focus on translational medicine and a wide range of scientific and soft-skill training. How to Apply

Please submit as a single pdf file:

(1) Letter of motivation

(2) Curriculum vitae

(3) Transcript of Records

(4) Summary of Research Experience and Master Project

(5) Letter of recommendation

 

Please submit applications via email to: c.guenther@uk-erlangen.de;

Application closing date is February 28th 2021.

For further information, visit our www.medizin1.uk-erlangen.de/en/forschung/research-groups/ag-prof-dr-rer-nat-claudia-guenther/