Publikationen

Lamprecht-Bailer R, Zundler S. Interventionelle endoskopische Therapie einer symptomatischen Leberzyste [Interventional endoscopic therapy of a symptomatic liver cyst]. Z Gastroenterol. 2025 Aug;63(8):833-835. German. doi: 10.1055/a-2596-8883. Epub 2025 Aug 4. PMID: 40759157.

Liu LJ, Müller TM, Dedden M, Schramm S, Leppkes M, Atreya R, Atreya I; TRR241 IBDome consortium; Neurath MF, Zundler S. ST6GAL1 promotes IBD B cell recruitment to the inflamed colon in a CD22-dependent mechanism. J Crohns Colitis. 2025 Jul 3;19(7):jjaf097. doi: 10.1093/ecco-jcc/jjaf097. PMID: 40491026.

Fischer S, Fischmann D, Wilde J, Vetter M, Wolf L, Geppert C, Atreya R, Waldner M, Strobel D, Neurath MF, Haberkamp S, Zundler S. IBUS-SAS Is a Highly Accurate Intestinal Ultrasound Score for Predicting Endoscopic Disease Activity in Ulcerative Colitis. United European Gastroenterol J. 2025 Sep;13(7):1253-1262. doi: 10.1002/ueg2.70053. Epub 2025 May 29. PMID: 40440217;
PMCID: PMC12463684.

Schmidt A, Fuchs J, Dedden M, Kocher K, Schülein C, Hübner J, Vieira Antão A, Irrgang P, Oltmanns F, Viherlehto V, Leicht N, Rieker RJ, Geppert C, Appelt U, Zundler S, Schober K, Lapuente D, Tenbusch M. Inflammatory conditions shape phenotypic and functional characteristics of lung-resident memory T cells in mice. Nat Commun. 2025 Apr 16;16(1):3612. doi: 10.1038/s41467-025-58931-y. PMID: 40240341; PMCID: PMC12003732.

Haberkamp S, Fischmann D, Wilde J, Fischer S, Vetter M, Wolf L, Vitali F, Klett D, Atreya R, Waldner M, Neurath MF, Strobel D, Zundler S. Accuracy of superb microvascular imaging (SMI) in predicting endoscopic Crohn's disease activity. Dig Liver Dis. 2025 Jun;57(6):1273-1279. doi: 10.1016/j.dld.2025.02.024. Epub 2025 Mar 22. PMID: 40121159.

Haberkamp S, Fischmann D, Wilde J, Strobel D, Vetter M, Wolf L, Vitali F, Klett D, Atreya R, Waldner M, Neurath MF, Fischer S, Zundler S. Superb Microvascular Imaging Is Superior to Doppler Imaging in Ruling Out Ulcerative Colitis Disease Activity. Inflamm Bowel Dis. 2025 Sep 1;31(9):2487-2494. doi: 10.1093/ibd/izaf033. PMID: 40056435.

Gerasimova E, Beenen AC, Kachkin D, Regensburger M, Zundler S, Blumenthal DB, Lutzny-Geier G, Winner B, Prots I. Novel co-culture model of T cells and midbrain organoids for investigating neurodegeneration in Parkinson's disease. NPJ Parkinsons Dis. 2025 Feb 28;11(1):36. doi: 10.1038/s41531-025-00882-8. PMID: 40021643; PMCID: PMC11871142.

Erkert L, Ruder B, Kabisch M, Gamez Belmonte R, Patankar JV, Gonzalez Acera M, Schödel L, Chiriac MT, Cineus R, Gnafakis S, Leupold T, Thoma OM, Stolzer I, Taut A, Thonn V, Zundler S, Günther C, Diefenbach A, Kühl AA, Hegazy AN, Waldner M, Basic M, Bleich A, Neurath MF, Wirtz S, Becker C; TRR241 IBDome Consortium. TIFA renders intestinal epithelial cells responsive to microbial ADP-heptose and drives colonic inflammation in mice. Mucosal Immunol. 2025 Apr;18(2):453-466. doi: 10.1016/j.mucimm.2025.01.003. Epub 2025 Jan 20. PMID: 39842611.

Machnik D, Fischer S, Vetter M, Lamprecht-Bailer R, Rouse-Merkel R, Klett D, Neurath MF, Strobel D, Zundler S, Haberkamp S. Risk factors associated with complications of palliative drainage of ascites with tunneled peritoneal catheters. Therap Adv Gastroenterol. 2025 Jan 10;18:17562848241310183. doi: 10.1177/17562848241310183. PMID: 39802628; PMCID: PMC11724411.

Orlemann T, Zundler S, Graetz T. Pneumatosis Intestinalis in Metastatic Colon Cancer During Cetuximab Treatment. Dtsch Arztebl Int. 2024 Nov 29;121(24):799. doi: 10.3238/arztebl.m2024.0148. PMID: 39902486; PMCID: PMC12442796.

Zundler S, Wolff K, Leppkes M, Gaza A, Haberkamp S, Strobel D, Siebler J, Neurath MF, Waldner M. Palliative treatment of malignant intestinal obstruction with EUS-guided ileosigmoidostomy - a case report. Z Gastroenterol. 2025 Mar;63(3):273-278. English. doi: 10.1055/a-2452-4337. Epub 2024 Nov 25. PMID: 39586810.

Vitali F, Heinrich M, Strobel D, Zundler S, Aghdassi AA, Uder M, Neurath MF, Grützmann R, Wiesmueller M, Frulloni L, Wildner D. Paraduodenal pancreatitis as diagnostic challenge: clinical and morphological features of patients with pancreatic pathology involving the pancreatic groove. Ann Gastroenterol. 2024 Nov-Dec;37(6):742-749. doi: 10.20524/aog.2024.0914. Epub 2024 Oct 20.
PMID: 39568705; PMCID: PMC11574150.

Müller TM, Liu LJ, Wiesinger M; TRR241 IBDome Consortium; Neurath MF, Voskens CJ, Zundler S. Engineering Therapeutic Regulatory T Cells to Overexpress G Protein-Coupled Receptor 15 Improves Functional Fitness for In Vivo Gut Homing. Gastroenterology. 2025 Feb;168(2):389-392.e4. doi: 10.1053/j.gastro.2024.10.003. Epub 2024 Oct 9. PMID: 39389186.

Wagner K, Müller TM, Vitali F, Fischer S, Haberkamp S, Rouse-Merkel R, Atreya R, Neurath MF, Zundler S. Treatment trajectories and outcomes in inflammatory bowel disease: a tertiary single-centre experience. Therap Adv Gastroenterol. 2024 Sep 28;17:17562848241284051. doi: 10.1177/17562848241284051. PMID: 39381754; PMCID: PMC11459667.

Horn V, Cancino CA, Steinheuer LM, Obermayer B, Fritz K, Nguyen AL, Juhran KS, Plattner C, Bösel D, Oldenburg L, Burns M, Schulz AR, Saliutina M, Mantzivi E, Lissner D, Conrad T, Mashreghi MF, Zundler S, Sonnenberg E, Schumann M, Haag LM, Beule D, Flatz L; TRR241 IBDome Consortium; Trajanoski Z, D'Haens G, Weidinger C, Mei HE, Siegmund B, Thurley K, Hegazy AN. Multimodal Profiling of Peripheral Blood Identifies Proliferating Circulating Effector CD4⁺ T Cells as Predictors for Response to Integrin α4β7-Blocking Therapy in Inflammatory Bowel Disease. Gastroenterology. 2025 Feb;168(2):327-343. doi: 10.1053/j.gastro.2024.09.021. Epub 2024 Sep 28. PMID: 39343250.

Roth D, Düll MM, Horst LJ, Lindemann A, Malzer X, Koop K, Zundler S, Vetter M, Jefremow A, Atreya R, Geppert C, Weidemann S, Waldner MJ, Dietrich P, Günther C, Munoz LE, Herrmann M, Scheffold A, Neurath MF, Siebler J, Schramm C, Kremer AE, Leppkes M. Integrin αVβ6: Autoantigen and Driver of Epithelial Remodeling in Colon and Bile Ducts in Primary Sclerosing Cholangitis and Inflammatory Bowel Disease. J Crohns Colitis. 2025 Feb 4;19(2):jjae131. doi: 10.1093/ecco-jcc/jjae131. PMID: 39212221.

Fererberger T, Buechler C, Kandulski A, Elger T, Loibl J, Schmid S, Sommersberger S, Gunawan S, Zundler S, Huss M, Bettenworth D, Kempa S, Weidlich S, Föh B, Huang X, Grzegorzek M,
Derer-Petersen S, Günther UL, Marquardt JU, Kunst C, Gülow K, Müller M, Sina C, Schmelter F, Tews HC. Distinct metabolomic and lipidomic profiles in serum samples of patients with primary sclerosing cholangitis. Front Med (Lausanne). 2024 Jun 4;11:1334865. doi:10.3389/fmed.2024.1334865. PMID: 38895187; PMCID: PMC11184724.

Sommer K, Garibagaoglu H, Paap EM, Wiendl M, Müller TM, Atreya I, Krönke G, Neurath MF, Zundler S. Discrepant Phenotyping of Monocytes Based on CX3CR1 and CCR2 Using Fluorescent Reporters and Antibodies. Cells. 2024 May 10;13(10):819. doi: 10.3390/cells13100819. PMID: 38786041; PMCID: PMC11119841.

Schenzel A, Geiger A, Nendel E, Yang Z, Krammer S, Leberle A, Brunst AK, Trump S, Mittler S, Rauh M, Geppert CI, Tausche P, Hohenberger K, Rieker RJ, Schieweck O, Zundler S, Finotto S. Fiber rich food suppressed airway inflammation, GATA3 + Th2 cells, and FcεRIα+ eosinophils in asthma. Front Nutr. 2024 May 2;11:1367864. doi: 10.3389/fnut.2024.1367864. PMID: 38757128;
PMCID: PMC11097976.

Wiendl M, Dedden M, Liu LJ, Schweda A, Paap EM, Ullrich KA, Hartmann L, Wieser L, Vitali F, Atreya I, Müller TM, Günther C, Atreya R, Neurath MF, Zundler S. Etrolizumab-s fails to control E-Cadherin-dependent co-stimulation of highly activated cytotoxic T cells. Nat Commun. 2024 Feb 3;15(1):1043. doi: 10.1038/s41467-024-45352-6. PMID: 38310086; PMCID: PMC10838339.

Schramm S, Liu LJ, Saad M, Dietz L, Dedden M, Müller TM, Atreya I, Voskens CJ, Atreya R, Neurath MF, Zundler S. Blocking GPR15 Counteracts Integrin-dependent T Cell Gut Homing in Vivo. J Crohns Colitis. 2024 Aug 6;18(7):1162-1172. doi: 10.1093/ecco-jcc/jjae012. PMID: 38243565.

Schulz-Kuhnt A, Rühle K, Javidmehr A, Döbrönti M, Biwank J, Knittel S, Neidlinger P, Leupold J, Liu LJ, Dedden M, Taudte RV, Gessner A, Fromm MF, Mielenz D, Kreiss L, Waldner MJ, Schürmann S,
Friedrich O, Dietel B, López-Posadas R, Plattner C; TRR241 IBDome Consortium; Zundler S, Becker C, Atreya R, Neurath MF, Atreya I. ATP citrate lyase (ACLY)-dependent immunometabolism in mucosal T cells drives experimental colitis in vivo. Gut. 2024 Mar 7;73(4):601-612. doi: 10.1136/gutjnl-2023-330543. PMID: 38176897.

Vitali F, Rath T, Klenske E, Vögele AL, Ganzleben I, Zundler S, Strobel D, Geppert C, Hartmann A, Neurath MF, Atreya R. Long-term outcomes of cyclosporin induction and ustekinumab maintenance combination therapy in patients with steroid-refractory acute severe ulcerative colitis. Therap Adv Gastroenterol. 2023 Dec 30;17:17562848231218555. doi: 10.1177/17562848231218555. PMID: 38164363; PMCID: PMC10757791.

Vitali F, Zundler S, Jesper D, Strobel D, Wildner D, de Pretis N, Frulloni L, Crinó SF, Neurath MF. Endoscopic Ultrasound in Pancreatology: Focus on Inflammatory Diseases and Interventions. Visc Med. 2023 Oct;39(5):131-139. doi: 10.1159/000533433. Epub 2023 Sep 5. PMID: 37899796; PMCID: PMC10601533.

Vitali F, Zundler S, Jesper D, Wildner D, Strobel D, Frulloni L, Neurath MF. Diagnostic Endoscopic Ultrasound in Pancreatology: Focus on Normal Variants and Pancreatic Masses. Visc Med. 2023 Oct;39(5):121-130. doi: 10.1159/000533432. Epub 2023 Sep 5. PMID: 37899794; PMCID: PMC10601528.

Chiriac MT, Hracsko Z, Günther C, Gonzalez-Acera M, Atreya R, Stolzer I, Wittner L, Dressel A, Schickedanz L, Gamez-Belmonte R, Erkert L, Hundorfean G, Zundler S, Rath T, Vetrano S, Danese S,
Sturm G, Trajanoski Z, Kühl AA, Siegmund B, Hartmann A, Wirtz S, Siebler J, Finotto S, Becker C, Neurath MF. IL-20 controls resolution of experimental colitis by regulating epithelial IFN/STAT2 signalling. Gut. 2024 Jan 5;73(2):282-297. doi: 10.1136/gutjnl-2023-329628. PMID: 37884352; PMCID: PMC10850655.

Rath T, Atreya R, Bodenschatz J, Uter W, Geppert CI, Vitali F, Zundler S, Waldner MJ, Hartmann A, Neurath MF. Healing of the epithelial barrier in the ileum is superior to endoscopic and histologic remission for predicting major adverse outcomes in ulcerative colitis. Front Med (Lausanne). 2023 Oct 10;10:1221449. doi: 10.3389/fmed.2023.1221449.
PMID: 37881628; PMCID: PMC10595008.

Weber S, Sitte S, Voegele AL, Sologub L, Wilfer A, Rath T, Nägel A, Zundler S, Franchi L, Opipari AW, Sonnewald S, Reid S, Hartmann A, Eichhorn P, Handtrack C, Weber K, Grützmann R, Neufert C,
Schellerer VS, Naschberger E, Ekici AB, Büttner C, Neurath MF, Atreya R. NLRP3 Inhibition Leads to Impaired Mucosal Fibroblast Function in Patients with Inflammatory Bowel Diseases. J Crohns Colitis. 2024 Mar 1;18(3):446-461. doi: 10.1093/ecco-jcc/jjad164. PMID: 37748021.

Cazorla-Vázquez S, Kösters P, Bertz S, Pfister F, Daniel C, Dedden M, Zundler S, Jobst-Schwan T, Amann K, Engel FB. Adhesion GPCR Gpr126 (Adgrg6) Expression Profiling in Zebrafish, Mouse, and
Human Kidney. Cells. 2023 Aug 2;12(15):1988. doi: 10.3390/cells12151988. PMID: 37566066; PMCID: PMC10417176.

Ullrich KA, Derdau J, Baltes C, Battistella A, Rosso G, Uderhardt S, Schulze LL, Liu LJ, Dedden M, Spocinska M, Kainka L, Kubánková M, Müller TM, Schmidt NM, Becker E, Ben Brahim O, Atreya I,
Finotto S, Prots I, Wirtz S, Weigmann B, López-Posadas R, Atreya R, Ekici AB, Lautenschläger F, Guck J, Neurath MF, Zundler S. IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells. Gut. 2023 Nov;72(11):2081-2094. doi: 10.1136/gutjnl-2023-329818. Epub 2023 Aug 4. PMID: 37541770; PMCID: PMC10579496.

Lindemann A, Roth D, Koop K, Neufert C, Zundler S, Atreya R, Neurath MF, Leppkes M. Protective effect of the novel calcineurin inhibitor voclosporin in experimental colitis. Front Med (Lausanne). 2023 Jun 9;10:1177450. doi: 10.3389/fmed.2023.1177450. PMID: 37358998; PMCID: PMC10289195.

Meitner-Schellhaas B, Jesper D, Goertz RS, Zundler S, Strobel D. Washout appearance of hepatocellular carcinomas using standardized contrast-enhanced ultrasound (CEUS) including an extended late phase observation - Real-world data from the prospective multicentre DEGUM study. Clin Hemorheol Microcirc. 2023;84(4):413-424. doi: 10.3233/CH-231740. PMID: 37334585.

Zundler S, Vitali F, Kharboutli S, Völkl S, Polifka I, Mackensen A, Atreya R, Neurath MF, Mougiakakos D. Case Report: IBD-like colitis following CAR T cell therapy for diffuse large B cell lymphoma.
Front Oncol. 2023 May 22;13:1149450. doi: 10.3389/fonc.2023.1149450. PMID: 37284193; PMCID: PMC10240064.

Schulze LL, Becker E, Dedden M, Liu LJ, van Passen C, Mohamed-Abdou M, Müller TM, Wiendl M, Ullrich KAM, Atreya I, Leppkes M, Ekici AB, Kirchner P, Stürzl M, Sexton D, Palliser D, Atreya R,
Siegmund B; TRR241 IBDome consortium; Neurath MF, Zundler S. Differential Effects of Ontamalimab Versus Vedolizumab on Immune Cell Trafficking in Intestinal Inflammation and Inflammatory Bowel Disease. J Crohns Colitis. 2023 Nov 24;17(11):1817-1832. doi: 10.1093/ecco-jcc/jjad088. PMID: 37208197.

Dedden M, Wiendl M, Müller TM, Neurath MF, Zundler S. Manual cell selection in single cell transcriptomics using scSELpy supports the analysis of immune cell subsets. Front Immunol. 2023 Apr 25;14:1027346. doi: 10.3389/fimmu.2023.1027346. PMID: 37180117; PMCID: PMC10166880.

Müller TM, Liu LJ, Czerwinski T, Wiesinger M, Dedden M, Paap EM, Ullrich KA, Atreya I, Siegmund B, Atreya R, Fabry B, Berking C, Neurath MF, Zundler S, Voskens CJ. Increased Motility and Suppression of Ex Vivo-Expanded Regulatory T Cells Designed for Adoptive Transfer Therapy in Ulcerative Colitis. Cell Mol Gastroenterol Hepatol. 2023;16(1):183-187.e2. doi: 10.1016/j.jcmgh.2023.04.002. Epub 2023 Apr 20. Erratum in: Cell Mol Gastroenterol Hepatol. 2025;19(10):101554. doi: 10.1016/j.jcmgh.2025.101554. PMID: 37085136; PMCID: PMC10285232.

Sommer K, Heidbreder K, Kreiss L, Dedden M, Paap EM, Wiendl M, Becker E, Atreya R, Müller TM, Atreya I, Waldner M, Schürmann S, Friedrich O, Neurath MF, Zundler S. Anti-β7 integrin treatment impedes the recruitment on non-classical monocytes to the gut and delays macrophage-mediated intestinal wound healing. Clin Transl Med. 2023 Apr;13(4):e1233. doi: 10.1002/ctm2.1233. PMID: 37029786; PMCID: PMC10082567.

Vetter M, Waldner MJ, Zundler S, Klett D, Bocklitz T, Neurath MF, Adler W, Jesper D. Artificial intelligence for the classification of focal liver lesions in ultrasound - a systematic review. Ultraschall Med. 2023 Aug;44(4):395-407. English. doi: 10.1055/a-2066-9372. Epub 2023 Mar 31. PMID: 37001563.

Strobel D, Agaimy A, Jesper D, Zundler S, Schellhaas B. HCCs lacking arterial phase hyperenhancement (APHE) on contrast-enhanced ultrasound (CEUS) - a diagnostic challenge. Findings from the prospective multicenter DEGUM CEUS HCC trial. Ultraschall Med. 2023 Dec;44(6):606-613. English. doi: 10.1055/a-2034-1911. Epub 2023 Feb 13. PMID: 36781161.

44: Heidbreder K, Sommer K, Wiendl M, Müller TM, Atreya I, Hildner K, Neurath MF, Zundler S. Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine. Front Immunol. 2023 Jan 18;13:1040775. doi: 10.3389/fimmu.2022.1040775. PMID: 36741412; PMCID: PMC9890957.

Zundler S, Schulze LL, Neurath MF. Controlling in and out - the future of interfering with immune cell trafficking in inflammatory bowel disease. Expert Rev Clin Immunol. 2023 Feb;19(2):155-167.
doi: 10.1080/1744666X.2023.2152794. Epub 2022 Dec 5. PMID: 36427088.

Zundler S, Mardin C, Bertz S, Vitali F, Strauß R, Fürst J, Neurath MF, Strobel D. Rectal Cancer Presenting with Absceding Infection Due to <i>Fusobacterium nucleatum</i>. Pathogens. 2022 Sep 28;11(10):1113. doi: 10.3390/pathogens11101113. PMID: 36297170; PMCID: PMC9609798.

Schneider I, Allner C, Mühl L, Melde M, Lissner D, Mantzivi E, Glauben R, Vitali F, Becker E, Atreya I, Müller TM, Atreya R, Siegmund B, Neurath MF, Zundler S. Expression and function of α4β7 integrin predict the success of vedolizumab treatment in inflammatory bowel disease. Transl Res. 2023 Mar;253:8-15. doi: 10.1016/j.trsl.2022.10.003. Epub 2022 Oct 20. PMID: 36272713.

Zundler S, Günther C, Kremer AE, Zaiss MM, Rothhammer V, Neurath MF. Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation. Nat Rev Gastroenterol Hepatol. 2023 Jan;20(1):50-64. doi: 10.1038/s41575-022-00663-1. Epub 2022 Aug 9. PMID: 35945456.

Leupold L, Sigutova V, Gerasimova E, Regensburger M, Zundler S, Zunke F, Xiang W, Winner B, Prots I. The Quest for Anti-α-Synuclein Antibody Specificity-Lessons Learnt From Flow Cytometry Analysis. Front Neurol. 2022 Jul 15;13:869103. doi: 10.3389/fneur.2022.869103. PMID: 35911883; PMCID: PMC9334871.

Schweda A, Becker E, Wiendl M, Atreya R, Atreya I, Müller TM, Neurath MF, Zundler S. Etrolizumab-s Does Not Induce Residual Trafficking of Regulatory T Cells. Inflamm Bowel Dis. 2022 Nov 2;28(11):1746-1755. doi: 10.1093/ibd/izac137. PMID: 35815779.

Besendorf L, Müller TM, Geppert CI, Schneider I, Mühl L, Atreya I, Vitali F, Atreya R, Neurath MF, Zundler S. Vedolizumab blocks α4β7 integrin-mediated T cell adhesion to MAdCAM-1 in microscopic colitis. Therap Adv Gastroenterol. 2022 Jun 28;15:17562848221098899. doi: 10.1177/17562848221098899. PMID: 35784193; PMCID: PMC9244938.

Kölle J, Zimmermann T, Kiefer A, Rieker RJ, Xepapadaki P, Zundler S, Papadopoulos NG, Finotto S. Targeted deletion of Interleukin-3 results in asthma exacerbations. iScience. 2022 May 23;25(6):104440. doi: 10.1016/j.isci.2022.104440. PMID: 35707726; PMCID: PMC9189047.

Becker E, Schweda A, Ullrich KA, Voskens C, Atreya R, Müller TM, Atreya I, Neurath MF, Zundler S. Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets. Clin Transl Gastroenterol. 2022 Jun 1;13(6):e00494. doi: 10.14309/ctg.0000000000000494. PMID: 35575178; PMCID: PMC9236604.

Voskens C, Stoica D, Rosenberg M, Vitali F, Zundler S, Ganslmayer M, Knott H, Wiesinger M, Wunder J, Kummer M, Siegmund B, Schnoy E, Rath T, Hartmann A, Hackstein H, Schuler-Thurner B,
Berking C, Schuler G, Atreya R, Neurath MF. Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis. Gut. 2023 Jan;72(1):49-53.
doi: 10.1136/gutjnl-2022-327075. Epub 2022 Apr 15. PMID: 35428657; PMCID: PMC9763232.

Voskens CJ, Stoica D, Roessner S, Vitali F, Zundler S, Rosenberg M, Wiesinger M, Wunder J, Siegmund B, Schuler-Thurner B, Schuler G, Berking C, Atreya R, Neurath MF. Safety and tolerability of a single infusion of autologous ex vivo expanded regulatory T cells in adults with ulcerative colitis (ER-TREG01): protocol of a phase 1, open-label, fast-track dose-escalation clinical trial. BMJ Open. 2021 Dec 8;11(12):e049208. doi: 10.1136/bmjopen-2021-049208. PMID: 34880013; PMCID: PMC8655533.

Melde M, Müller TM, Schneider I, Geppert CI, Mühl L, Besendorf L, Allner C, Becker E, Atreya I, Vitali F, Atreya R, Neurath MF, Zundler S. α4β7 integrin-dependent adhesion of T cells to MAdCAM-1 is blocked by vedolizumab in patients with chronic refractory pouchitis. Therap Adv Gastroenterol. 2021 Nov 24;14:17562848211054707. doi: 10.1177/17562848211054707. PMID: 34868349; PMCID: PMC8640978.

Leppkes M, Lindemann A, Gößwein S, Paulus S, Roth D, Hartung A, Liebing E, Zundler S, Gonzalez-Acera M, Patankar JV, Mascia F, Scheibe K, Hoffmann M, Uderhardt S, Schauer C, Foersch S,
Neufert C, Vieth M, Schett G, Atreya R, Kühl AA, Bleich A, Becker C, Herrmann M, Neurath MF. Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis. Gut. 2022 Dec;71(12):2414-2429. doi: 10.1136/gutjnl-2021-324725. Epub 2021 Dec 3. PMID: 34862250; PMCID: PMC9667856.

Zundler S. Zellmigration als therapeutischer Zielprozess. Drug Res (Stuttg). 2021 Nov;71(S 01):S26-S27. German. doi: 10.1055/a-1606-5983. Epub 2021 Nov 17. PMID: 34788886.

Jesper D, Fiedler S, Klett D, Waldner MJ, Schellhaas B, Zundler S, Neurath MF, Pfeifer L. Shear Wave Dispersion Imaging for the Characterization of Focal Liver Lesions - A Pilot study. Ultraschall Med. 2022 Oct;43(5):507-513. English. doi: 10.1055/a-1610-9171. Epub 2021 Oct 6. PMID: 34614516.

Strobel D, Haberkamp S, Zundler S. Portal Vein Thrombosis due to Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT) after Covid Vaccination with ChAdOx1 nCoV-19. Ultraschall Med. 2021 Oct;42(5):551-552. English. doi: 10.1055/a-1579-9303. Epub 2021 Oct 1. PMID: 34598301. 

Becker E, Dedden M, Gall C, Wiendl M, Ekici AB, Schulz-Kuhnt A, Schweda A, Voskens C, Hegazy A, Vitali F, Atreya R, Müller TM, Atreya I, Neurath MF, Zundler S. Residual homing of α4β7-expressing β1⁺PI16⁺ regulatory T cells with potent suppressive activity correlates with exposure-efficacy of vedolizumab. Gut. 2022 Aug;71(8):1551-1566.
doi: 10.1136/gutjnl-2021-324868. Epub 2021 Aug 30. PMID: 34462337.

Patankar JV, Müller TM, Kantham S, Acera MG, Mascia F, Scheibe K, Mahapatro M, Heichler C, Yu Y, Li W, Ruder B, Günther C, Leppkes M, Mathew MJ, Wirtz S, Neufert C, Kühl AA, Paquette J,
Jacobson K, Atreya R, Zundler S, Neurath MF, Young RN, Becker C. E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis. Nat Cell Biol. 2021 Jul;23(7):796-807. doi: 10.1038/s41556-021-00708-8. Epub 2021 Jul 8. PMID: 34239062.

Enderle K, Dinkel M, Spath EM, Schmid B, Zundler S, Tripal P, Neurath MF, Hildner K, Neufert C. Dynamic Imaging of IEL-IEC Co-Cultures Allows for Quantification of CD103-Dependent T Cell Migration. Int J Mol Sci. 2021 May 13;22(10):5148. doi: 10.3390/ijms22105148. PMID: 34067987; PMCID: PMC8152227.

Wiendl M, Becker E, Müller TM, Voskens CJ, Neurath MF, Zundler S. Targeting Immune Cell Trafficking - Insights From Research Models and Implications for Future IBD Therapy. Front Immunol. 2021 May 4;12:656452. doi: 10.3389/fimmu.2021.656452. PMID: 34017333; PMCID: PMC8129496.

Müller TM, Becker E, Wiendl M, Schulze LL, Voskens C, Völkl S, Kremer AE, Neurath MF, Zundler S. Circulating Adaptive Immune Cells Expressing the Gut Homing Marker α4β7 Integrin Are Decreased in COVID-19. Front Immunol. 2021 Apr 20;12:639329. doi: 10.3389/fimmu.2021.639329. PMID: 33959123; PMCID: PMC8093414.

Vitali F, Simon D, Neurath MF, Schett G, Zundler S. Vedolizumab-associated enthesitis: correlation or causality? Rheumatology (Oxford). 2021 Dec 1;60(12):5491-5492.
doi: 10.1093/rheumatology/keab396. PMID: 33930133.

Sommer K, Wiendl M, Müller TM, Heidbreder K, Voskens C, Neurath MF, Zundler S. Intestinal Mucosal Wound Healing and Barrier Integrity in IBD-Crosstalk and Trafficking of Cellular Players. Front Med (Lausanne). 2021 Mar 23;8:643973. doi: 10.3389/fmed.2021.643973. PMID: 33834033; PMCID: PMC8021701.

Paap EM, Müller TM, Sommer K, Neurath MF, Zundler S. Total Recall: Intestinal T_RM Cells in Health and Disease. Front Immunol. 2021 Jan 19;11:623072.
doi: 10.3389/fimmu.2020.623072. PMID: 33542725; PMCID: PMC7851044.

Fischer S, Cohnen S, Klenske E, Schmitt H, Vitali F, Hirschmann S, Ramming A, Zundler S, Rath T, Krebs S, Dörje F, Uter W, Nagore D, Meyer S, Neurath MF, Atreya R. Long-term effectiveness, safety and immunogenicity of the biosimilar SB2 in inflammatory bowel disease patients after switching from originator infliximab. Therap Adv Gastroenterol. 2021 Jan 14;14:1756284820982802. doi:10.1177/1756284820982802. PMID: 33505519; PMCID: PMC7812413.

Mühl L, Becker E, Müller TM, Atreya R, Atreya I, Neurath MF, Zundler S. Clinical experiences and predictors of success of treatment with vedolizumab in IBD patients: a cohort study. BMC Gastroenterol. 2021 Jan 22;21(1):33. doi: 10.1186/s12876-021-01604-z. PMID: 33482730; PMCID: PMC7821503.

Ullrich KA, Schulze LL, Paap EM, Müller TM, Neurath MF, Zundler S. Immunology of IL-12: An update on functional activities and implications for disease. EXCLI J. 2020 Dec 11;19:1563-1589.
doi: 10.17179/excli2020-3104. PMID: 33408595; PMCID: PMC7783470.

Patankar JV, Chiriac MT, Lehmann M, Kühl AA, Atreya R, Becker C; Callaborators; Gonzalez-Acera M, Schmitt H, Gamez-Belmonte R, Mahapatro M, Diemand L, Hartmann L, Mascia F, Hracsko Z,
Thonn V, Schödel L, Zielinska M, Yu Y, Erkert L, Li W, Zeitler M, Ruder B, Ganzleben I, Günther C, Voehringer D, Zundler S, Neurath MF, Siegmund B. Severe Acute Respiratory Syndrome Coronavirus 2 Attachment Receptor Angiotensin-Converting Enzyme 2 Is Decreased in Crohn's Disease and Regulated By Microbial and Inflammatory Signaling. Gastroenterology. 2021 Feb;160(3):925-928.e4.
doi: 10.1053/j.gastro.2020.10.021. Epub 2020 Oct 17. PMID: 33075345; PMCID: PMC7567698.

Gerlach K, Lechner K, Popp V, Offensperger L, Zundler S, Wiendl M, Becker E, Atreya R, Rath T, Neurath MF, Weigmann B. The JAK1/3 inhibitor tofacitinib suppresses T cell homing and activation in chronic intestinal inflammation. J Crohns Colitis. 2021 Feb 1;15(2):jjaa162. doi: 10.1093/ecco-jcc/jjaa162. Epub 2020 Aug 18. PMID: 32808031.

Schulz-Kuhnt A, Greif V, Hildner K, Knipfer L, Döbrönti M, Zirlik S, Fuchs F, Atreya R, Zundler S, López-Posadas R, Neufert C, Ramming A, Kiefer A, Grüneboom A, Strasser E, Wirtz S, Neurath MF,
Atreya I. ILC2 Lung-Homing in Cystic Fibrosis Patients: Functional Involvement of CCR6 and Impact on Respiratory Failure. Front Immunol. 2020 May 7;11:691. doi: 10.3389/fimmu.2020.00691.
PMID: 32457736; PMCID: PMC7221160.

Zundler S, Tauschek V, Neurath MF. Immune Cell Circuits in Mucosal Wound Healing: Clinical Implications. Visc Med. 2020 Apr;36(2):129-136. doi: 10.1159/000506846. Epub 2020 Mar 13.
PMID: 32355670; PMCID: PMC7184832.

Allner C, Melde M, Becker E, Fuchs F, Mühl L, Klenske E, Müller L, Morgenstern N, Fietkau K, Hirschmann S, Atreya R, Atreya I, Neurath MF, Zundler S. Baseline levels of dynamic CD4⁺ T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study. BMC Gastroenterol. 2020 Apr 15;20(1):103. doi: 10.1186/s12876-020-01253-8. PMID: 32293299; PMCID: PMC7158080.

Zundler S. Utilization of Diagnostic Imaging and Ionizing Radiation Exposure-Has the Tide Already Turned? Inflamm Bowel Dis. 2020 May 12;26(6):907-908. doi: 10.1093/ibd/izz220.
PMID: 31560037.

López-Posadas R, Fastancz P, Martínez-Sánchez LDC, Panteleev-Ivlev J, Thonn V, Kisseleva T, Becker LS, Schulz-Kuhnt A, Zundler S, Wirtz S, Atreya R, Carlé B, Friedrich O, Schürmann S, Waldner MJ, Neufert C, Brakebusch CH, Bergö MO, Neurath MF, Atreya I. Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4β7 and Development of Colitis in Mice. Gastroenterology. 2019 Nov;157(5):1293-1309. doi: 10.1053/j.gastro.2019.07.007. Epub 2019 Jul 11. PMID: 31302143.

Zundler S, Becker E, Schulze LL, Neurath MF. Immune cell trafficking and retention in inflammatory bowel disease: mechanistic insights and therapeutic advances. Gut. 2019 Sep;68(9):1688-1700. doi: 10.1136/gutjnl-2018-317977. Epub 2019 May 24. PMID: 31127023.

Schleier L, Wiendl M, Heidbreder K, Binder MT, Atreya R, Rath T, Becker E, Schulz-Kuhnt A, Stahl A, Schulze LL, Ullrich K, Merz SF, Bornemann L, Gunzer M, Watson AJM, Neufert C, Atreya I, Neurath MF, Zundler S. Non-classical monocyte homing to the gut via α4β7 integrin mediates macrophage-dependent intestinal wound healing. Gut. 2020 Feb;69(2):252-263. doi: 10.1136/gutjnl-2018- 316772. Epub 2019 May 15. PMID: 31092589.

Schulz-Kuhnt A, Zundler S, Grüneboom A, Neufert C, Wirtz S, Neurath MF, Atreya I. Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy. J Vis Exp. 2019 Apr 16;(146). doi: 10.3791/59043. PMID: 31058894.

Zundler S, Becker E, Spocinska M, Slawik M, Parga-Vidal L, Stark R, Wiendl M, Atreya R, Rath T, Leppkes M, Hildner K, López-Posadas R, Lukassen S, Ekici AB, Neufert C, Atreya I, van Gisbergen KPJM, Neurath MF. Author Correction: Hobit- and Blimp-1-driven CD4⁺ tissue-resident memory T cells control chronic intestinal inflammation. Nat Immunol. 2019 Apr;20(4):514.
doi: 10.1038/s41590-019-0360-y. Erratum for: Nat Immunol. 2019 Mar;20(3):288-300. doi: 10.1038/s41590-018-0298-5. PMID: 30846879.

Lichnog C, Klabunde S, Becker E, Fuh F, Tripal P, Atreya R, Klenske E, Erickson R, Chiu H, Reed C, Chung S, Neufert C, Atreya I, McBride J, Neurath MF, Zundler S. Cellular Mechanisms of Etrolizumab Treatment in Inflammatory Bowel Disease. Front Pharmacol. 2019 Feb 1;10:39. doi: 10.3389/fphar.2019.00039. PMID: 30774593; PMCID: PMC6367223.

Zundler S, Becker E, Spocinska M, Slawik M, Parga-Vidal L, Stark R, Wiendl M, Atreya R, Rath T, Leppkes M, Hildner K, López-Posadas R, Lukassen S, Ekici AB, Neufert C, Atreya I, van Gisbergen KPJM, Neurath MF. Hobit- and Blimp-1-driven CD4⁺ tissue-resident memory T cells control chronic intestinal inflammation. Nat Immunol. 2019 Mar;20(3):288-300. doi: 10.1038/s41590-018-0298-5. Epub 2019 Jan 28. Erratum in: Nat Immunol. 2019 Apr;20(4):514. doi: 10.1038/s41590-019-0360-y. PMID: 30692620.

Zundler S, Dietz L, Matzel KE, Geppert CI, Becker E, Rath T, Neurath MF, Atreya R. Successful Long-term Treatment of Diversion Colitis with Topical Coconut Oil Application. Am J Gastroenterol. 2018 Dec;113(12):1908-1910. doi: 10.1038/s41395-018-0394-z. Epub 2018 Oct 23. PMID: 30353052; PMCID: PMC6768601.

Becker E, Schramm S, Binder MT, Allner C, Wiendl M, Neufert C, Atreya I, Neurath M, Zundler S. Dynamic Adhesion Assay for the Functional Analysis of Anti-adhesion Therapies in Inflammatory Bowel Disease. J Vis Exp. 2018 Sep 20;(139):58210. doi: 10.3791/58210. PMID: 30295649; PMCID: PMC6235239.

Binder MT, Becker E, Wiendl M, Schleier L, Fuchs F, Leppkes M, Atreya R, Neufert C, Atreya I, Neurath MF, Zundler S. Similar Inhibition of Dynamic Adhesion of Lymphocytes From IBD Patients to MAdCAM-1 by Vedolizumab and Etrolizumab-s. Inflamm Bowel Dis. 2018 May 18;24(6):1237-1250. doi: 10.1093/ibd/izy077. PMID: 29788362.

Ullrich E, Abendroth B, Rothamer J, Huber C, Büttner-Herold M, Buchele V, Vogler T, Longerich T, Zundler S, Völkl S, Beilhack A, Rose-John S, Wirtz S, Weber GF, Ghimire S, Kreutz M, Holler E,
Mackensen A, Neurath MF, Hildner K. BATF-dependent IL-7RhiGM-CSF+ T cells control intestinal graft-versus-host disease. J Clin Invest. 2018 Mar 1;128(3):916-930. doi: 10.1172/JCI89242.
Epub 2018 Jan 29. PMID: 29376889; PMCID: PMC5824870.

Zundler S, Klingberg A, Schillinger D, Fischer S, Neufert C, Atreya I, Gunzer M, Neurath MF. Three-Dimensional Cross-Sectional Light-Sheet Microscopy Imaging of the Inflamed Mouse Gut. Gastroenterology. 2017 Oct;153(4):898-900. doi: 10.1053/j.gastro.2017.07.022. Epub 2017 Sep 4. PMID: 28870528.

Zundler S, Strobel D, Manger B, Neurath MF, Wildner D. Pancreatic Panniculitis and Polyarthritis. Curr Rheumatol Rep. 2017 Aug 26;19(10):62. doi: 10.1007/s11926-017-0690-4. PMID: 28844095.

Zundler S, Becker E, Weidinger C, Siegmund B. Anti-Adhesion Therapies in Inflammatory Bowel Disease-Molecular and Clinical Aspects. Front Immunol. 2017 Jul 28;8:891.
doi: 10.3389/fimmu.2017.00891. PMID: 28804488; PMCID: PMC5532375.

Fuchs F, Schillinger D, Atreya R, Hirschmann S, Fischer S, Neufert C, Atreya I, Neurath MF, Zundler S. Clinical Response to Vedolizumab in Ulcerative Colitis Patients Is Associated with Changes in Integrin Expression Profiles. Front Immunol. 2017 Jul 3;8:764. doi: 10.3389/fimmu.2017.00764. PMID: 28717358; PMCID: PMC5495081.

Zundler S, Neurath MF. Pathogenic T cell subsets in allergic and chronic inflammatory bowel disorders. Immunol Rev. 2017 Jul;278(1):263-276. doi: 10.1111/imr.12544. PMID: 28658546.

Zundler S, Neurath MF. Novel Insights into the Mechanisms of Gut Homing and Antiadhesion Therapies in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2017 Apr;23(4):617-627.
doi: 10.1097/MIB.0000000000001067. PMID: 28296823.

Zundler S, Fischer A, Schillinger D, Binder MT, Atreya R, Rath T, Lopez-Pósadas R, Voskens CJ, Watson A, Atreya I, Neufert C, Neurath MF. The α4β1 Homing Pathway Is Essential for Ileal Homing of Crohn's Disease Effector T Cells In Vivo. Inflamm Bowel Dis. 2017 Mar;23(3):379-391. doi: 10.1097/MIB.0000000000001029. PMID: 28221249.

Zundler S, Schillinger D, Fischer A, Atreya R, López-Posadas R, Watson A, Neufert C, Atreya I, Neurath MF. Blockade of αEβ7 integrin suppresses accumulation of CD8⁺ and Th9 lymphocytes from patients with IBD in the inflamed gut in vivo. Gut. 2017 Nov;66(11):1936-1948. doi: 10.1136/gutjnl-2016-312439. Epub 2016 Aug 19. PMID: 27543429.

19: Atreya I, Diall A, Dvorsky R, Atreya R, Henninger C, Grün M, Hofmann U, Schaeffeler E, López-Posadas R, Daehn I, Zenker S, Döbrönti M, Neufert C, Billmeier U, Zundler S, Fritz G, Schwab M,
Neurath MF. Designer Thiopurine-analogues for Optimised Immunosuppression in Inflammatory Bowel Diseases. J Crohns Colitis. 2016 Oct;10(10):1132-43. doi: 10.1093/ecco-jcc/jjw091.
Epub 2016 Apr 25. PMID: 27112707.

Zundler S, Neurath MF. Integrating Immunologic Signaling Networks: The JAK/STAT Pathway in Colitis and Colitis-Associated Cancer. Vaccines (Basel). 2016 Feb 29;4(1):5.
doi: 10.3390/vaccines4010005. PMID: 26938566; PMCID: PMC4810057.

Zundler S, Erber R, Agaimy A, Hartmann A, Kiesewetter F, Strobel D, Neurath MF, Wildner D. Pancreatic panniculitis in a patient with pancreatic-type acinar cell carcinoma of the liver--case report and review of literature. BMC Cancer. 2016 Feb 20;16:130. doi: 10.1186/s12885-016-2184-6. PMID: 26895632; PMCID: PMC4761203.

Zundler S, Caioni M, Müller M, Strauch U, Kunst C, Woelfel G. K+ Channel Inhibition Differentially Regulates Migration of Intestinal Epithelial Cells in Inflamed vs. Non-Inflamed Conditions in a PI3K/Akt-Mediated Manner. PLoS One. 2016 Jan 29;11(1):e0147736. doi: 10.1371/journal.pone.0147736. PMID: 26824610; PMCID: PMC4732808.

Zundler S, Neurath MF. How will new and future therapies change our treatment of IBD? Expert Rev Clin Immunol. 2016;12(3):233-6. doi: 10.1586/1744666X.2016.1112271.
Epub 2015 Nov 11. PMID: 26558407.

Zundler S, Neurath MF. Immunopathogenesis of inflammatory bowel diseases: functional role of T cells and T cell homing. Clin Exp Rheumatol. 2015 Jul-Aug;33(4 Suppl 92):S19-28.
Epub 2015 Oct 12. PMID: 26458165.

Fischer A, Zundler S, Atreya R, Rath T, Voskens C, Hirschmann S, López-Posadas R, Watson A, Becker C, Schuler G, Neufert C, Atreya I, Neurath MF. Differential effects of α4β7 and GPR15 on homing of effector and regulatory Tcells from patients with UC to the inflamed gut in vivo. Gut. 2016 Oct;65(10):1642-64. doi: 10.1136/gutjnl-2015-310022. Epub 2015 Jul 24. PMID: 26209553;
PMCID: PMC5036234.

Zundler S, Neurath MF. Interleukin-12: Functional activities and implications for disease. Cytokine Growth Factor Rev. 2015 Oct;26(5):559-68. doi: 10.1016/j.cytogfr.2015.07.003.
Epub 2015 Jul 4. PMID: 26182974.